منابع مشابه
Childhood Conditions and Exceptional Longevity
A number of previous studies found interesting links between the early-life experiences and a subsequent mortality in later life. Such findings justify further advancement of these studies by exploring possible links between childhood conditions and exceptional longevity (survival to 100 years). However a number of methodological issues have to be resolved (such as data availability, quality, a...
متن کاملThe epidemiology of longevity and exceptional survival.
The field of the "epidemiology of longevity" has been expanding rapidly in recent years. Several long-term cohort studies have followed older adults long enough to identify the most long-lived and to define many factors that lead to a long life span. Very long-lived people such as centenarians have been examined using case-control study designs. Both cohort and case-control studies have been th...
متن کاملDynamic Determinants of Longevity and Exceptional Health
It is well known from epidemiology that values of indices describing physiological state in a given age may influence human morbidity and mortality risks. Studies of connection between aging and life span suggest a possibility that dynamic properties of age trajectories of the physiological indices could also be important contributors to morbidity and mortality risks. In this paper we use data ...
متن کاملResilience Significantly Contributes to Exceptional Longevity
Objective. We aim to investigate whether centenarians are significantly more resilient than younger elders and whether resilience significantly contributes to exceptional longevity. Data. We use a unique dataset from the Chinese Longitudinal Healthy Longevity Survey with the largest sample to date of centenarians, nonagenarians, octogenarians, and a compatible group of young old aged 65-79. Met...
متن کاملGenetic Signatures of Exceptional Longevity in Humans
Healthy aging is thought to reflect the combined influence of environmental factors (lifestyle choices) and genetic factors. To explore the genetic contribution, we undertook a genome-wide association study of exceptional longevity (EL) in 1055 centenarians and 1267 controls. Using these data, we built a genetic model that includes 150 single-nucleotide polymorphisms (SNPs) and found that it co...
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ژورنال
عنوان ژورنال: Journal of Heredity
سال: 1916
ISSN: 1465-7333,0022-1503
DOI: 10.1093/oxfordjournals.jhered.a110621